There is only way to be safe from the diseases that are being spread by sexually active people: ABSTINENCE. Abstinence means not having sex or engaging in sexual relationships. This is the only way to ensure your own personal safety. Abstinence is the only way for people to be safe from sexual diseases. There are many deadly and devastating diseases that can be spread by sex. Sex is reserved for marriage. Sex within marriage is pure and holy, without disease or victimization.